Synthetic Biology





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Confirmed speakers


Prof. Lars M. Blank
Institute of Applied Microbiology, IAMB, Germany

Prof. L. M. Blank from the Institute of Applied Microbiology (iAMB) of the RWTH Aachen is an (co-)author of more than 120 Metabolic Engineering and Synthetic Biology publications. His work on Metabolic Engineering and Synthetic Biology includes the creation of microorganisms for the production of chemicals and proteins. Examples range from small molecules like malate, to glycolipids, and polymers. One of the tools used for quantification of microbial physiology is stable isotope-based metabolic flux analysis. In general, Lars M. Blank focuses in his research on fundamental and applied aspects of microbial metabolism. Of specific interest is the interaction between the metabolic network and the introduced genetic and environmental perturbations. The research on in silico/in vivo metabolic network operation is aimed at a deeper understanding of cell function, with the ultimate goal of rational cell engineering.

Dr. Pascale Daran-Lapujade
Delft University of Technology, Netherlands

Pascale Daran-Lapujade obtained her PhD from the INPL (Nancy, France) in 2000 and joined the Industrial Microbiology section at the Delft University of Technology (The Netherlands) as assistant professor in 2005. In 2018 she has been appointed full Professor of Experimental Systems Biology. Her research focuses on addressing fundamental questions relevant for the development of efficient cell factories. At the interface of quantitative physiology, cell biology, synthetic biology and systems biology approaches, her research has contributed in obtaining a deeper fundamental understanding of the mechanisms employed by the industrial and model yeast S. cerevisiae to adapt to its environment.  In the past 6 years, her research has taken a new turn in developing synthetic yeast platforms with modular genomes that enable the fast, combinatorial exploration, and optimization of the biological function of essential cellular processes.

Dr. Xavier Garrabou Pi
ETH Zurich, Switzerland

Xavier Garrabou Pi received his B.S. degree in Chemistry from the Ramon Llull University (Barcelona, 2004), and in 2005 he joined the research team of Prof. Pere Clapés at IQAC-CSIC (Barcelona). He received his Ph.D. degree in Biotechnology from the University of Barcelona (2010), and in 2011 he moved to ETH Zürich as a postdoctoral fellow with Prof. Donald Hilvert. Since 2018, he is developing artificial enzymes for industrial applications as a Pioneer Fellow with the support of the ETH Zurich Foundation. His current field of interest is the de novo creation and engineering of enzymes as catalysts for abiological carboligation reactions.

Dr. Carole Lartigue
International Institute of Agronomic Research, INRA, France

Dr Carole Lartigue received her doctorate in 2003 from the university Victor Segalen in Bordeaux, France. In 2004, she joined the JCVI Synthetic Biology team and contributed to the transplantation of the engineered M. mycoides genome into M. capricolum. Using genome transplantation technology and genome assembly methods, the synthetic biology team achieved their final goal of creating a cell controlled by a synthetic genome in 2010. In 2010, Carole returned back to INRA, Bordeaux (France) as senior scientist where she continues to expand the utility of bacterial genome transplantation in Mycoplasmas and to better understand the interaction of mycoplasmas with their hosts. C. Lartigue received in 2014 the Derrick Edward Award, (Young Researcher Award) from the International Organization for Mycoplasmology.

Dr. Karen Polizzi
Imperial College London, INRA, UK

Dr. Karen Polizzi is a Reader in Biotechnology in the Department of Chemical Engineering at Imperial College London.  She has spent her career working at the interface of biological sciences and engineering, training first as a biochemist (BSc, University of Maine) and then a chemical engineer (PhD, Georgia Institute of Technology). In 2008, Karen joined Imperial College as an RCUK Fellow in Biopharmaceutical Processing.  Karen’s research focuses on the application of synthetic biology to the development of biological systems for manufacturing including cell-based and cell-free production.



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