University of Natural Resources and Life Sciences & Austrian Centre of Industrial Biotechnology, Austria
Nicole Borth, PhD (Biotechnology, University of Life Sciences Vienna, Austria 1991), is Professor of Cell Biology and Cytometry at the Department of Biotechnology, University of Life Sciences Vienna (BOKU) and Area Leader in the Austrian Center of Industrial Biotechnology ACIB. Her research aims at obtaining a comprehensive understanding of the molecular machinery that enables mammalian cells to be good production factories for biotherapeutic proteins. Using methods such as genomics, transcriptomics, flow cytometry / cell sorting and computational biology, her group aims at dissecting the molecular basis and regulation of process and quality relevant cellular properties. Nicole is a co-chair of http://www.CHOgenome.org, a non-profit organization that makes genome scale information for CHO cells publicly available. She is also an executive committee member of ESACT, the European Society of Animal Cell Technology.
bio: BOKU Staff
University of California, USA
Dr. Lewis is an Associate Professor of Pediatrics and Bioengineering at the University of California, San Diego. He received his training in biochemistry at Brigham Young University, bioengineering at UC San Diego, and genome editing at the Wyss Institute at Harvard Medical School, where he focused on omics and big data analysis using systems biology modeling techniques. Dr. Lewis’ lab has since led efforts to develop systems biology models of mammalian metabolism and the secretory pathway. His group is utilizing these resources to study protein synthesis and secretion in mammalian cells to engineer desired traits into recombinant protein producing cells.
Imperial College London, UK
Dr Francesca Ceroni graduated in Pharmaceutical Biotechnologies from the University of Bologna, Italy, in 2007. She then obtained a PhD in Bioengineering from the same university in 2011 working in the field of synthetic biology on the development of synthetic genetic devices in prokaryotic and eukaryotic cells for the control of cellular functions. In 2010, she was Visiting Research Fellow in the Laboratory of Professor Pam Silver, in the Department of Systems Biology at the Harvard Medical School of Boston, USA. She worked together with Dr. Karmella Haynes to build a synthetic device for real-time detection of microRNAs in cancer cells. In January 2013 Francesca joined Imperial College London as Research Associate in Synthetic Biology in the groups of Dr. Tom Ellis and Dr. Guy-Bart Stan within the Centre for Synthetic Biology. Her work aimed at examining the causes of cellular burden in Escherichia coli when transformed with foreign genetic devices in order to understand the host response to recombinant protein production and identify design rules for synthetic systems. In 2016 Francesca was awarded the prestigious Imperial College Junior Research Fellowship to pursue her interests in mammalian synthetic biology for bioproduction and healthcare applications. From October 2018 Francesca is Lecturer in the Department of Chemical Engineering at Imperial College London. She is now continuing her work on bacterial and mammalian cells for the characterisation of host-construct interactions.
Biberach University of Applied Sciences, Germany
Kerstin Otte is a trained biologist and obtained her PhD at the SL-University Uppsala, Sweden. After a postdoctoral fellowhip at the Gurdon Institute in Cambridge, UK, she joined the biotech industry in Heidelberg, Germany for preclinical drug development. Kerstin Otte now holds a professorship at the Biberach University, Germany, focusing her research on biopharmaceutical cell line development.
UCB Celltech, United Kingdom
More information soon.